miRNA description for hsa-mir-4488
miRNA accession	hsa-mir-4488
Species	Homo sapiens
hsa-mir-4488 identified in exosomes derived from the following tissue/cell type
Chronic lymphocytic leukemia cells [Exosomes]	26100252
Colorectal cancer cells [Small extracellular vesicles]	34887515
Colorectal cancer cells [Exomeres]	34887515
Colorectal cancer cells [Supermeres]	34887515
Posterior longitudinal ligament [Small extracellular vesicles]	35513391
Posterior longitudinal ligament [Small extracellular vesicles]	35513391
Experiment description of studies that identified hsa-mir-4488 in exosomes
1 Experiment ID 898 Identified molecule miRNA Identification method RNA sequencing PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name CLL cells Molecules identified in the study miRNA Methods used in the study RNA sequencing EV-TRACK EV150015: EV-METRIC:22%, 44%
2 Experiment ID 3338 Identified molecule miRNA Identification method RNA sequencing PubMed ID 34887515    Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry RNA sequencing EV-TRACK -
3 Experiment ID 3339 Identified molecule miRNA Identification method RNA sequencing PubMed ID 34887515    Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry ELISA RNA sequencing EV-TRACK -
4 Experiment ID 3340 Identified molecule miRNA Identification method RNA sequencing PubMed ID 34887515    Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry ELISA RNA sequencing EV-TRACK -
5 Experiment ID 2739 Identified molecule miRNA Identification method RNA sequencing PubMed ID 35513391    Organism Homo sapiens Experiment description Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 Authors Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W. Journal name Nat Commun Publication year 2022 Sample Posterior longitudinal ligament Sample name Ossicifation of posterior longitudinal ligament cells Molecules identified in the study Protein miRNA Methods used in the study Western blotting RNA sequencing qRT-PCR EV-TRACK -
6 Experiment ID 2740 Identified molecule miRNA Identification method RNA sequencing PubMed ID 35513391    Organism Homo sapiens Experiment description Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 Authors Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W. Journal name Nat Commun Publication year 2022 Sample Posterior longitudinal ligament Sample name Posterior longitudinal ligament cells Molecules identified in the study miRNA Methods used in the study RNA sequencing qRT-PCR EV-TRACK -